Clinical trials provide essential evidence to guide the care of patients with kidney disease. As the global burden of kidney disease is growing, the ISN recognises the importance of supporting clinical trials around the world.

This toolkit is aimed at nephrologists and researchers in nephrology from all parts of the globe – regardless of their level of clinical trial experience and their local resources. It aims to provide a guidance for anyone wishing to start a clinical trial or to participate as a trial site.

The toolkit was developed by the ISN-ACT toolkit working group led by Brendan Smyth, David Wheeler and Thomas Hiemstra. Membership of the ISN-ACT Toolkit Working Group can be found here


Study Stages

Stage I:

Design and development

Stage II:

Ethics and regulatory requirements

Stage III:

Conducting a trial

Stage IV:

Analysis and reporting

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