ISN Frontiers meetings build on the success and achievements of the ISN Nexus and Forefronts series, bringing together basic scientists, clinicians and practitioners in a unique setting. This new event format will make more cutting-edge science available to a global audience, breaking down cross-regional barriers in accessing the latest knowledge and expertise.

ISN Frontiers Bergamo

Bergamo, Italy | July 1-3, 2021

The ISN and the Mario Negri Institute for Pharmacological Research are pleased to invite you to the 2021 ISN Frontiers Meeting in ‘Complement-related kidney diseases: classification, genetics, and treatment’ to be held from July 1-3, 2021, in Bergamo, Italy.

The 2021 Frontiers Meeting will focus on the two prototypical complement-mediated kidney diseases: atypical hemolytic uremic syndrome (aHUS) and C3 Glomerulopathies /Membranoproliferative Glomerulonephritis (C3G/MPGN), both very rare and severe diseases. aHUS is an ultra-rare disease with an estimated prevalence of 1/100,000, while primary C3G/MPGN has an estimated prevalence of 16/100,000.

Despite current available treatments, key issues regarding diagnosis and genetic assessment remain a challenge. An analysis of knowledge advancement is urgently required to identify key issues relevant to the optimal management of these two diseases and to propose a research agenda to resolve outstanding controversial issues.

The meeting will gather a global panel of clinical and scientific expertise and will bring together clinicians, scientists, academics, and general practitioners to share and present the latest developments in terms of differential diagnosis, disease classification, genetics, and identifying knowledge gaps and unmet treatment needs.

There is an urgent clinical need to precisely characterize the underlying pathogenetic mechanisms in each patient to identify the target molecule within the complex complement cascade and the suitable inhibitor among those in the clinical pipeline.

Vivek Jha   Giuseppe Remuzzi Marina Noris Raja Ramachandran
ISN President   Scientific Program Working Group Chairs


Past Frontiers, Forefronts and Nexus symposia

Frontiers symposia

Kidney Disease and Cardiovascular Disease February 22-25, 2018 Tokyo, Japan For the symposium program please click here.
For the ISN events presentations and top ten abstracts please visit the ISN Academy.


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