Additional Resources
- Evidence-Informed Cloth Masks: find guidance on how to make/clean/put on and take off a cloth mask.
- World Health Organization's COVID-19 site with updates and clinical information
- Global
MediXchange for Combating COVID
a compilation of Chinese experience. "This platform was established to facilitate continued communication and collaboration across borders, as well as to provide the necessary computing capabilities and data intelligence to empower pivotal research efforts. The platform can provide frontline medical teams with the necessary communication channels to share practical experience and information about fighting the pandemic." - Doctors of the World UK, COVID-19 advice for patients in 21 languages, "produced in partnership with the British Red Cross, Migrant Help and Clear Voice: English, Albanian, Dari, French, Pashto, Portuguese, Bengali, Vietnamese, Kurdish Sorani is available at the moment, but more languages coming soon: Mandarin, Hindi, Urdu, Arabic, Spanish, Portuguese, Malayalam, Turkish, Farsi, Amharic, Tigrinya, Somali"
- Coronavirus
tracked: the latest figures as the pandemic spreads
Open Access resource from The Financial Times - #Masks4All
How to make a mask - Coronavirus
- guidance for anesthesia and perioperative care providers
Resources provided by The World Federation of Societies of Anaesthesiologists - RSM COVID-19 Series: For health professionals, by
health professionals
This series has been developed to support and unite all healthcare workers on the frontlines with senior decision makers leading the response in this critical fight against COVID-19, as we navigate the challenges presented by the pandemic. Chaired by leading experts, these webinars discuss different topics and challenges that healthcare workers, leaders and the public are facing, and how we are responding.
A. Handling Dialysis during the COVID-19 pandemic
- Haemodialysis Unit Preparedness Checklist developed
to deliver safe dialysis during and after COVID-19 pandemic
A checklist to help dialysis units prepare for possible arrival of patients with COVID-19 by The George Institute for Global Health - Frontline
health workers in COVID-19 prevention and control: rapid evidence synthesis
A rapid review of global evidence in a systematic manner to inform decision making contextualised to context by The George Institute for Global Health
For additional information, visit The George Institute for Global Health - US Centers for Disease Control and Prevention (CDC) guidance for patients on outpatient dialysis
- Staying Safe During Dialysis and the COVID-19 Outbreak – National Kidney Foundation
- Preventive measures in haemodialysis centre of Policlinico Milan
during COVID-19 Epidemic
Description of the preventive measures put in action in the dialysis centre at the Policlinico of Milan since the very beginning of the start of the COVID19 epidemic. - Recomendações
de Boas Práticas da Sociedade Brasileira de Nefrologia
In Portuguese. Recommendations from the Brazilian Society of Nephrology - COVID-19
Flowchart
Used by the Nephrology & Renal Transplantation Unit in Leuven, Belgium; and by the International Renal Research Institute, San Bortolo Hospital, Vicenza, Italy. Provided by Dr. Björn Meijers - Recomendações para pacientes pediátricos em hemodálise
Guidelines for pediatric patients in dialysis, peritoneal dialysis and transplanted patients by the Brazilian Society of Nephrol - Strategies
regarding COVID-19 in PD patients.From the ISPD Standards and Guidelines Committee
The ISPD Standards and Guidelines Committee has been working to adapt the recommendation of the Peking University First Hospital for PD patients during the COVID-19 crisis. Also available in many other languages - Management Of Patients On Dialysis And With Kidney Transplant During SARS-COV-2 (COVID-19) Pandemic In Brescia, Italy
- Organization of Preventive Measures against COVID-19 Infection Dissemination in the Nephrology HD
Centers
Russian Version
English translation - Coronavirus destroys lungs. But doctors are finding its damage in kidneys, hearts and elsewhere
- Protocol
for haemodialysis unit in covid 19 pandemic
safety of health care workers and patients during haemodialysis incovid 19 pandemic in dialysis unit from pgimer, chandigargh
- Conceptos actuales sobre el compromiso del riñón en la pandemia coronavirus 19 (Sars CoV-2)
- The Chilean Kidney Education Foundation, a non-profit organization linked to the Chilean Society of Nephrology, has created a digital platform open to the community to support, guide, and educate patients with CKD
- Colombian consensus SARS-CoV-2 / COVID-19 infection in people with Chronic Kidney Disease; C10 resources
- COVID-19 Guidance from the Transplant Infectious Disease Section of The Transplantation Society
- EL RIÑÓN
EN LA PANDEMIA DEL CORONAVIRUS-19
In Spanish: Summary description of The Novel Coronavirus 2019 epidemic and kidneys - Protocolo de
orientação para colegas que cuidem de pacientes portadores de doenças renais raras em
virtude da epidemia da sars cov2 . In Portuguese.
Guidelines for rare renal diseases by the Brazilian Society of Nephrology - Please visit the SLANH
website for materials on COVID-19.
SLANH has shared the two resources below on caring for renal patients during COVID-19: - Guidance for clinicians with patients receiving
immunosuppression treatment for autoimmune conditions of their native kidneys during COVID-19-
from The Renal Association
A printable PDF version of this page is available here
To provide therapeutic guidance on the management of patients receiving immunosuppression for autoimmune conditions. - Stratified risk for prolonged self isolation for
adults and children who are receiving immunosuppression for disease of their native kidneys
The RA renal risk stratification for which renal patients in this group should be in prolonged self isolation (also called shielding) can be found at: https://renal.org/stratified-risk-prolonged-self-isolation-adults-children-receiving-immunosuppression-disease-native-kidneys/ - Coronavirus
guidance for patients with kidney disease. From Kidney Care-UK
The latest news and information on COVID-18 for kidney patients - Resources
from ERA-EDTA
COVID-19, the Novel Corona Virus – New and information for the ERA-EDTA community and kidney patients - The ASN
resource page
Resources provided by the ASN - COVID-19 dashboard from TTS
Addresses the important information needs of the international professional transplant community during this pandemic. - Russian Dyalisis Society
ISN Journals
- An initial report from the French SOT COVID Registry
suggests high mortality due to Covid-19 in recipients of kidney transplants.
Notwithstanding the ongoing coronavirus disease-2019 (Covid-19) pandemic, information on its clinical presentation and prognosis in recipients of a kidney transplant remain scanty. The aim of this registry-based observational study was to explore characteristics and clinical outcomes of recipients of kidney transplants included in the French nationwide Registry of Solid Organ Transplant Recipients with Covid-19 - Challenges
in setting up point-of-care hemodialysis in a COVID-19 care facility: Lessons from a
limited-resource setting
Dialysis care is one amongst the many health-care activities to be severely affected by coronavirus disease 2019 (COVID-19). Further, health-care facilities in limited-resource settings are challenged with unique problems warranting distinct strategies to combat this crisis. Our administrator was summoned to set up a state-of-the art facility for managing infected patients in a jiffy - De
Novo ANCA-associated Vasculitis with Glomerulonephritis in COVID-19
Coronavirus Disease 2019 (COVID-19) is a pandemic, caused by a novel coronavirus that has been identified to belong to the beta-coronavirus family.1 As the COVID-19 pandemic continues to evolve, more aspects of this illness are being defined and described. In the US, the incidence of acute kidney injury (AKI) in patients hospitalized with COVID-19, has been reported to be around 37%.2 Different autopsy and kidney biopsy series have revealed acute tubular injury (ATI) to be the most common renal pathology lesion in these patients. - IgA
Vasculitis with Nephritis (Henoch-Schönlein purpura) in a COVID-19 patient
In December 2019, a series of pneumonia cases of unknown etiology, which were epidemiologically linked to a seafood market, was reported in Wuhan, Hubei province, China. The disease has rapidly spread around the world, becoming a global pandemic. A coronavirus, which was named 2019 novel coronavirus (2019-nCov), was isolated from respiratory tract samples1 and later identified as SARS-CoV-2. The name of the disease was officially changed to Coronavirus Disease 2019 (COVID-19). - Dashboards
to facilitate nephrology disaster planning in the COVID-19 era
The emergence of the coronavirus disease 2019 (COVID-19) pandemic has placed tremendous stress on health care systems. While there was early recognition of the need for rapid upscaling and sourcing for ventilatory support, the need for renal replacement therapy (RRT) resource planning due to the high incidence of acute kidney injury (AKI) was not widely anticipated. - Outcomes of patients with end-stage kidney disease hospitalized with
COVID-19
Given the high risk of infection-related mortality, patients with end-stage kidney disease (ESKD) may be at increased risk with COVID-19. To assess this, we compared outcomes of patients with and without ESKD, hospitalized with COVID-19. This was a retrospective study of patients admitted with COVID-19 from 13 New York. hospitals from March 1, 2020, to April 27, 2020, and followed through May 27, 2020. - SARS-CoV-2 Causes a Specific Dysfunction of the Kidney Proximal
Tubule
LCoronavirus disease 2019 (COVID-19) is commonly associated with kidney damage, and the angiotensin converting enzyme 2 (ACE2) receptor for SARS-CoV-2 is highly expressed in the proximal tubule cells. Whether patients with COVID-19 present specific manifestations of proximal tubule dysfunction remains unknown. To test this, we examined a cohort of 49 patients requiring hospitalization in a large academic hospital in Brussels, Belgium. - Acute
kidney injury associated with lopinavir/ritonavir combined therapy in patients with COVID-19
Lopinavir and low-dose ritonavir are associated in a fixed-dose combination protease inhibitor therapy (LPV/RTV), indicated against human immunodeficiency virus infection (HIV) and acquired immune deficiency syndrome. The recent outbreak of severe acute respiratory syndrome coronavirus 2 infections causing coronavirus disease 2019 (Covid-19) has rekindled the interest in LPV/RTV, following preclinical studies. - Steroids:
A Therapeutic Option for COVID-19 Pneumonia Patients With ESRD?
Alberici et al.1 proposed in a recent review some therapeutic approaches for patients with end-stage renal disease and infected with coronavirus disease 2019 (COVID-19). They notably suggest the use of steroids during the inflammatory phase of the disease, even if their efficacy is currently being debated - Treatment Impact on COVID-19 evolution in hemodialysis patients
We retrospectively studied 248 patients on maintenance hemodialysis (MHD) affected by COVID-19 (1) in 19 private and academic MHD centers of the Paris, France area. - Peritoneal
Dialysis for Acute Kidney Injury during the COVID-19 Pandemic in New York City
The Coronavirus disease 2019 (COVID-19) pandemic resulted in extraordinary increase in the number of patients requiring Renal replacement Therapy (RRT), high rate of clotting in Continuous Renal Replacement Therapy (CRRT) circuits, limited dialysis supplies and shortages of dialysis staff due to illness or quarantine. - Epidemiological,
Clinical, and Immunological Features of a Cluster of COVID-19–Contracted Hemodialysis Patients
The outbreak of highly contagious coronavirus disease 2019 (COVID-19) has posed a serious threat to human life and health, especially for those with underlying diseases. However, the impact of COVID-19 epidemic on hemodialysis (HD) centers and HD patients has not been reported. - Kidney International and the COVID-19 infection
The Editorial Team of Kidney International would like to reassure our readership that we will continue to bring you highquality information throughout the COVID19 pandemic to help all of us deal with the crisis and provide high-quality care to our patients. - Coronavirus disease 2019 (COVID-19) hospitalized patients with acute
kidney injury treated with acute peritoneal dialysis do not have infectious peritoneal dialysis
effluent
Acute peritoneal dialysis (PD) has been used in coronavirus disease 2019 (COVID-19) as an alternative to intermittent hemodialysis or continuous renal replacement therapy to mitigate the overwhelming demand for dialysis. - Thrombotic microangiopathy in a patient with COVID-19
We describe a patient with coronavirus disease 2019 (COVID-19) and clinically significant kidney biopsy-proven thrombotic microangiopathy. - Rapid resolution of cytokine release syndrome and favorable clinical
course of severe COVID-19 in a kidney transplant recipient treated with tocilizumab
Immunomodulatory drugs, such as tocilizumab, hold promise for the management of cytokine release syndrome in coronavirus disease 2019 (COVID-19). - Management
of Patients on Dialysis and With Kidney Transplantation During the SARS-CoV-2 (COVID-19)
Pandemic in Brescia, Italy
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus disease (COVID-19), is a major pandemic challenging health care systems around the world. - Hypercoagulability and anticoagulation in patients
with COVID-19 requiring renal replacement therapy
Severe acute respiratory coronavirus 2 (SARS-CoV2) and the resulting acute respiratory distress syndrome (COVID-19) is responsible for a worldwide pandemic, with over 10 million cases reported as of 28th June 2020. - COVID-19 and ESRD: Entering a New Era of Uncertainty
The SARS-CoV-2 (COVID-19) pandemic has raised our awareness of the susceptibility to certain members of the population to this serious and often fatal infection. - The Cumulative Rate of
SARS-CoV-2 Infection in Chinese Hemodialysis Patients
There is a paucity of information regarding SARS-CoV-2 infection in patients undergoing maintenance hemodialysis. We aimed to estimate the cumulative attack rate of SARS-CoV-2 in hemodialysis patients in China using a serological test. - COVID-19 in patients on
maintenance dialysis in the Paris Region
COVID-19 represents a serious threat to patients on maintenance dialysis. The clinical setting, mortality rate and prognostic factors in these patients have not been well established. - SARS-Cov-2 virions or
ubiquitous cell structures? Actual dilemma in COVID-19 era
Several reports have suggested ultrastructural evidence of direct infection of different types of kidney cells by SARS-CoV-2 in post-mortem analysis and kidney biopsy specimens in patients with proven viral RT-PCR from nasopharyngeal smears. Detection of supposed viral particles by transmission electron microscopy (TEM) was used as sufficient evidence for viral invasion of renal tissue but data regarding detection of viral RNA or other valuable methods for viral detection of kidney specimens were missing - Hydroxychloroquine-associated
Hypoglycemia in Hemodialysis Patients with COVID-19
Coronavirus Disease 2019 (COVID-19) is a global health problem, but optimal treatment modality is unclear. The treatment protocol for patients with COVID-19 consists of azithromycin, hydroxychloroquine (HCQ), and low-molecular-weight heparin in our center. - Transient Renal Tubular
Syndromes Associated with Acute COVID-19 Disease
We report two transient renal tubular syndromes associated with COVID19 disease. - Interleukin 6 levels after tocilizumab administration
in transplant recipients with COVID-19
It is with great interest we read the article by Gautier-Vargas and colleagues that reported favorable clinical response with tocilizumab in a kidney transplant recipient with severe coronavirus disease 2019 (COVID-19) - The adverse effect of
COVID pandemic on the care of patients with kidney diseases in India
The Coronavirus disease-19 (COVID-19) pandemic has affected the care of patients with non-communicable diseases, including those suffering from kidney-related ailments. Many parts of the world, including India, adopted lockdown to curb community transmission of disease. The lockdown affected transportation, access to healthcare facilities, availability of medicines, and consumables as well as out and inpatient services. We aimed to analyze the effect of lockdown imposed due to COVID-19 pandemic on the care of patients with kidney diseases in India - Dashboards to facilitate nephrology disaster planning
in the COVID-19 era
The emergence of the Coronavirus Disease 2019 (COVID-19) pandemic has placed tremendous stress on healthcare systems. While there was early recognition of the need for rapid upscaling and sourcing for ventilatory support, the need for renal replacement therapy (RRT) resource planning due to the high incidence of acute kidney injury (AKI) was not widely anticipated. - Reduced prescription tacrolimus use: A
cross-sectional analysis of England’s national prescription statistics during COVID-19 pandemic
by region
Many United Kingdom transplant centres currently provide restricted access due to COVID-19. Full-year total organ transplants were 3997 in 2019/20 versus 4183 in the previous year, a fall of 4.45% - A Systematic Review and Meta-Analysis Of Outcomes for
Patients with COVID-19 and Acute Kidney Injury
There is limited data on the association of kidney dysfunction with prognosis in COVID-19, and the extent to which acute kidney injury (AKI) predisposes patients to severe illness and inferior outcomes is unclear. We aim to assess the incidence of AKI among patients with COVID-19 and examine their associations with patient outcomes as reported in the available literature thus far. - A view from the front line of the COVID-19 war
Just a few weeks ago, I was looking at kidney biopsy slides through the microscope. As a nephrologist with a special interest in renal histopathology, I never thought I would soon find myself at the front line in the coronavirus disease 2019 (COVID-19) pandemic. - COVID-19 in dialysis patients: adding a few more
pieces to the puzzle
Maintenance hemodialysis (MHD) patients are at increased risk for coronavirus disease 2019 (COVID-19) and its complications, owing to the presence of multiple comorbid conditions. The logistical aspects within a dialysis facility further increase the risk of disease transmission - A report from the Brescia Renal COVID Task Force on the clinical
characteristics and short-term outcome of hemodialysis patients with SARS-CoV-2 infection
The SARS-CoV-2 epidemic is pressuring healthcare systems worldwide. Disease outcomes in certain subgroups of patients are still scarce, and data are needed. Therefore, we describe here the experience of four dialysis centers of the Brescia Renal COVID Task Force. - COVID-19: clinical course and outcomes of 36 hemodialysis patients in
Spain
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia emerged in Wuhan, China in December 2019. Unfortunately, there is a lack of evidence about the optimal management of novel coronavirus disease 2019 (COVID-19), and even less is available in patients on maintenance hemodialysis therapy than in the general population. - Preparedness of Kidney Replacement Therapy in the
Critically Ill During COVID-19 Surge
The devastating and rapidly spreading coronavirus disease 2019 (COVID-19) pandemic has challenged the health care system worldwide. COVID-19 primarily affects the lungs and is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); however, multiple other organ systems also may be affected, including kidneys, blood (hypercoagulability), brain, and heart. - Delivering dialysis during the COVID-19 outbreak:
Strategies and outcomes
Haemodialysis (HD) patients are at increased risk of COVID-19 infection. Although all dialysis patients meet government criteria for shielding, only those on home treatment can comply. Patients attending incentre HD units represent a large and vulnerable group, who are unable to rigorously adhere to this advice - The case of Complement activation in COVID-19
multiorgan impact
The novel coronavirus disease COVID-19 originates in the lungs, but may extend to other organs, causing, in severe cases, multiorgan damage, including cardiac injury and acute kidney injury. In severe cases, the presence of kidney injury is associated with increased risk of death, highlighting the relevance of this organ as a target of SARS-CoV-2 infection. - COVID-19 outbreak in a large hemodialysis centre in
Lombardy, Italy
On December 31, 2019, China reported the first cases of pneumonia of unknown cause that would later be identified as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (1-3). SARS-CoV2 rapidly spread, resulting in a pandemic, and as of April 10, 2020 there were almost 1.6 million confirmed cases were reported worldwide, with approximately 97,200 deaths. - Kidney biopsy findings in a critically ill COVID-19
patient with dialysis-dependent acute kidney injury: a case against “SARS-CoV-2 nephropathy”
It is unclear whether in patients with SARS-CoV-2 infection, acute kidney injury (AKI) results from direct infection of the kidneys or from complications arising in the course of COVID-19. Reports of urinary abnormalities in COVID-19 patientsS1, positive staining of tubules with viral antigens and complement components in one autoptic series1, visualization of viral particles in tubular epithelial cells and podocytes on ultrastructural examination in another2, and isolation of SARS-CoV-2 in urineS2,S3, raised the possibility of a “SARS-CoV-2 nephropathy”. - SARS-CoV2 in the peritoneal waste in a patient treated with
peritoneal dialysis
We describe for the first time the detection of SARS-CoV2 in the peritoneal waste of a patient with COVID19 and end-stage-kidney-disease on peritoneal dialysis - Acute Kidney Injury In Patients Hospitalized With
Covid-19
The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. - De-isolation of COVID-19– positive hemodialysis patients in the
outpatient setting: Q1 a single-center experience
The advice for patients presenting with COVID-19 symptoms is to self-isolate for 7 days after the onset of symptoms for the individual case and 14 days for the household.1 Dialysis patients can be considered as immunocompromised and display a decreased ability to develop seroconversion to infectious diseases. - A report from the Brescia Renal COVID Task Force on
the clinical characteristics and short-term outcome of hemodialysis patients with SARS-CoV-2
infection
The SARS-CoV-2 epidemic is pressuring health care systems worldwide. Disease outcomes in certain subgroups of patients are still scarce, and data are needed. The report describes the experience of four dialysis centers of the Brescia Renal COVID task force. - COVID-19: Clinical course and outcomes of 36
maintenance hemodialysis patients from a single center in Spain.
SARS-CoV-2-pneumonia emerged in Wuhan, China in December 2019. Unfortunately, there is lack of evidence about the optimal management of novel coronavirus disease 2019 (COVID-19), even less in patients on maintenance hemodialysis (MHD) therapy than in the general population. - Autophagy inhibition by chloroquine and
hydroxychloroquine could adversely affect AKI and other organ injury in critically ill patients
with COVID-19
We read the letter by Izzedine et al (1) with great interest especially the discussion of renal adverse effects of drug treatment options for COVID-19. We would like to draw particular attention to the potential adverse effect of chloroquine and hydroxychloroquine, the lysosomotropic antimalarial drugs that may inhibit the infection of SARS-CoV-2 by reducing the entry and replication of the virus. - Multivesicular Bodies (MVB) Mimicking SARS-CoV-2 in patients without
COVID-19
It is now well known that patients with novel coronavirus disease (COVID-19) due to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) commonly have kidney complications, including acute kidney injury, proteinuria, and hematuria - Visualization of Putative Coronavirus in Kidney
We read with concern the articles that report the presence of coronavirus in kidney based on electron microscopic evidence (1, 2). Neither article, in fact, demonstrates the presence of coronavirus in the kidney. - Acute Kidney Injury Due to Collapsing Glomerulopathy
Following COVID-19 Infection
Article presents a case of CG associated with COVID-19 in the initial days of the epidemic’s spread to New York City, and summarizes that, “As we learn more about the renal manifestations of COVID-19, we should keep in mind the possibility of CG among COVID-19 patients with proteinuria and acute kidney injury, even among those with mild respiratory disease.” - Adding insult to injury: kidney replacement therapy
during COVID-19 in India
The report describes the unique hardships confronted by maintenance in-center hemodialysis patients and kidney transplant recipients in India during the current lockdown period. - Letter to the Editor: Collapsing glomerulopathy in a COVID-19 patient
The first available reports indicate that renal involvement is relatively frequent in patients with novel coronavirus disease (COVID-19) due to the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the exact mechanisms underlying renal injury in patients with COVID-19 are unclear as renal pathology data are lacking. - Early Experience with COVID-19 in Kidney Transplantation
Visual Abstract - COVID-19 infection in kidney transplant recipients
Visual Abstract - A single center observational study of the clinical characteristics and short-term outcome of 20 kidney transplant patients admitted for SARS-CoV2 pneumonia
- Collapsing Glomerulopathy in a Patient with
Coronavirus Disease 2019 (COVID-19)
This case raises the question of whether people of African descent with high-risk APOL1 genotype (presence of two risk alleles) could be at increased risk of kidney disease in the setting of COVID-19. - Renal histopathological analysis of 26 postmortem findings of patients with COVID-19 in China
- Managing the COVID-19 Pandemic: International
Comparisons in Dialysis Patients
As new information appears, updated guidance produces many similarities, and some differences in these guidance documents, in part deriving from regional and population differences. This article reviews guidance for detecting and mitigating COVID-19 infections in dialysis patients, noting where there is universal agreement and where there are differences. - Blockade of SARS-CoV-2 infection by recombinant
soluble ACE2
Viruses use specific host-cell plasma membrane molecules as receptors to enter the cell. SARS-CoV-2, the coronavirus responsible for the current COVID-19 pandemic, is believed to bind mainly or exclusively to angiotensin-converting enzyme 2 (ACE2). ACE2 activity per se does not seem to be involved in infectivity, but its role in pulmonary, cardiac and kidney function has putative consequences for disease severity. - The Novel Coronavirus 2019 epidemic and kidneys
- Could ferritin help the screening for COVID-19 in
hemodialysis patients?
Screening for COVID-19 in hemodialysis centers is crucial to then isolate infected patients and protect non-infected patients. Ferritin could be a helpful, available and easy to use screening tool for the disease, although we believe that more research is still needed. - SARS-CoV-2
Infection in Hospitalized Patients with Kidney Disease
Since the outbreak of coronavirus disease 2019 (COVID-19) in December 2019, the disease has spread rapidly across the globe. Up to April 1, 2020, there have been 823,626 confirmed cases and 40,598 deaths. Actual case fatality ratio is still unknown but some studies have reported ranges between 1.4%—3.8%. - COVID-19-Associated Collapsing Glomerulopathy: An
Emerging Entity
Coronavirus Disease 2019 (COVID-19) is an emerging human infectious disease caused by a novel β coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Clinical manifestations range from asymptomatic infection, self-limited flu-like symptoms, to severe acute pneumonia with high mortality. - Tubuloreticular inclusions in COVID-19-related collapsing
glomerulopathy
A 79-year-old male of African ancestry, with a history of hemorrhagic stroke, monoclonal gammopathy of unknown significance and chronic kidney disease stage 3 due to hypertension was admitted to Bichat hospital on day 1 after the first symptom of COVID-19 (fever). SARS-CoV 2 PCR was positive on nasal swab. At admission urinary dipstick was normal and plasma creatinine was 224 μmol/L. On day 4 plasma albumin was at 29 g/L and proteinuria was 11.4 g per gram of urinary creatinine (80% of albumin). - Assessing and improving the capacity of district health services in the management of Acute Kidney Injury in low and middle-income countries
- COVID-19 and the
Renin-Angiotensin System
In late 2019, a coronavirus disease (COVID-19) leading to Severe Acute Respiratory Syndrome (SARS) started in China and has become a pandemic. The responsible virus has been designated SARS-CoV-2. The cellular receptor for SARS-CoV-2 is angiotensin-converting-enzyme 2 (ACE2), a mostly membrane-bound homologue of angiotensin converting enzyme (ACE) that has generated great interest in the interaction between COVID-19 and the renin-angiotensin system (RAS)1, as well as in the medicines commonly used to block the RAS. - Kidney
disease is associated with in-hospital death of patients with COVID-19
Yichun Cheng, Ran Luo, Kun Wang, Meng Zhang, Zhixiang Wang, Lei Dong, Junhua Li, Ying Yao, Shuwang Ge, Gang Xu - COVID-19 therapeutic options for patients with Kidney Disease
Hassan Izzedine, Kenar D. Jhaveri, Mark A. Perazella
- COVID-19 Guidance for People with Hypertension From
the World Hypertension League
Description: In order to provide some guidance to people with hypertension on how to best protect themselves from the novel coronavirus, COVID-19, the World Hypertension Executive has created the attached document, "COVID-19 Guidance for People with Hypertension", based on studies currently available - Managing COVID-19 for people with NCDs
The resources below provide the latest information for people living with NCDs and their carers.- COVID-19 and Respiratory Diseases
- COVID-19 and Cardiovascular Diseases
- COVID-19 and Diabetes
- COVID-19 and Cancer
- COVID-19 and Dementia
- COVID-19
and Obesity
Resources from The European Association for the Study of Obesity
- Coronavirus:
The Science Explained From UK Research and Innovation
A good general purpose resource - COVID-19
Open Research Dataset with information on COVID-19 and coronavirus-related research (e.g.
SARS, MERS, etc.) from the following sources
- PubMed's PMC open access corpus on COVID-19
- Additional COVID-19 research articles from a corpus maintained by the WHO
- bioRxiv and medRxiv pre-prints
- NEJM COVID-19
literature
A collection of articles and other resources on the Coronavirus (Covid-19) outbreak, including clinical reports, management guidelines, and commentary. - JAMA
Coronavirus Resource Centre
Browse the JAMA Network COVID-19 collection below, including Q&A's with NIAID's Anthony Fauci, an interactive map of the outbreak courtesy of The Johns Hopkins Center for Systems Science and Engineering, and past publications on vaccine development, infection control, and public health preparedness. - COVID-19
at the Lancet
This resource brings together new 2019 novel coronavirus disease (COVID-19) content from across The Lancet journals as it is published. - Kidney
diseases in the time of COVID-19: major challenges to patient care. In The Journal of Clinical
Investigation
In this viewpoint, the author discusses a number of kidney-specific aspects of COVID-19 infection, noting therapeutic and basic research opportunities - Renal
Impairment in COVID-19. A Review. By Raúl Lombardi MD
a short review of 13 papers with data on frequency of AKI, RRT, associated mortality, as well as the value of urine protein for early diagnosis of renal injury in COVID-19 patients.
- Addressing
COVID-19 Face Mask Shortages
Information provided by the Stanford Medicine Anesthesia Informatics and Media Lab - Ethical Framework for Health Care Institutions
Responding to Novel Coronavirus SARS-CoV-2 (COVID-19). From The Hastings Center
Guidelines for Institutional Ethics Services Responding to COVID-19 - Ethical dimensions of COVID-19 for front-line staff.
From the Royal College of Physicians
The Royal College of Physicians has published ethical guidance for frontline staff dealing with the COVID-19 pandemic, supported by more than a dozen other health organizations.